“A microRNA switch regulates the rise in hypothalamic GnRH…” 5/2/16 The microRNA switch linked fixation of a specific amino acid substitution in microtubules to cognition and to vertebrate behavior via achiral glycine in position 6 of the GnRH decapeptide. See: GnRH replacement rescues cognition in Down syndrome 9/2/22 Co-authors include Ulrich Boehm with senior author … The physics of existence (8)
Intranasal Administration of miR-146a Agomir Rescued the Pathological Process and Cognitive Impairment in an AD Mouse Model 10/10/19 …the nasal-to-brain pathway is efficient and operable for the administration of miRNAs to treat brain diseases (Figure 8). All brain diseases are included. See also: Pheromones…for inducing proliferation of neural stem cells and neurogenesis For microRNA-mediated suicide … MicroRNAs on Veteran’s Day 2019
Summary: Confused researchers at Rockefeller should meet with Bruce McEwen to learn why he said my 1992 model of biophysically constrained cell type differentiation could not be validated unless I started with gene activation in GnRH neurosecretory neurons of hypothalamus. A replacement for the hypothesis-free pseudoscience touted by biologically uninformed theorists was published on September … The ‘confusant’ hypothesis
Common Allele Linked to Sugar Consumption Leads to Lower Body Fat, Higher Blood Pressure One energy-dependent change in a base pair is linked from the FGF21 rs838133 variant to microRNA-mediated changes in morphology and behavior. The quantized energy as information link from microRNAs to morphology and behavior is common to my mouse-to-human model of sympatric speciation. … The eternal significance of microRNAs (1)
Summary: Slide number 6 clearly states the “Levels of Biological Organization” that the “NSF’s 10 Big Ideas” finally places into the context of what has been known to all serious scientists for more than a century. Simply put, Hugo de Vries definition of mutation (sudden energy jumps) should never have been accepted as anything besides … Laws of Biology / Rules of Life
The link from the quantized energy of sunlight to the creation of microRNAs and biophysically constrained morphological phenotypes has been clear since 1944, when Schroedinger placed it into the context of “What is Life?”. In the reprint edition, Roger Penrose added: “How often do we still hear that quantum effects can have little relevance in … MicroRNAs biophysically constrain behavior
Creating biophysically constrained viral latency (2) Serious scientists have reached the point where they are finally ready to expose the pseudoscientific nonsense during Evolution – Genetic Novelty/Genomic Variations by RNA Networks and Viruses and also during Schrödinger at 75 – The Future of Biology – September 2018. Until then, pseudoscientists may want to see these examples of … Creating biophysically constrained viral latency (2)
Summary: The tenacity of energy-dependent life extends from quantum physics to quantum souls via what is known about the birds and the bees (and bacteria). Simply put, if they don’t eat, they die. Neuroscience—and the new weapons of the mind Dietary modification also shows increasing promise for the exogenous manipulation of neurotransmitter signaling. Recent research … Eating electrons and excreting degraded energy
Why is natural selection hard to grasp? It is not what you think…. …human cognitive tendencies interfere more with deep understanding of how natural selection works. Simply put, our intelligence and teleological reasoning interferes with the teaching of pseudoscientific nonsense. The nonsense does not place Darwin’s “conditions of life” before natural selection for reproductive fitness. … Natural selection for racism and all pathology
Summary: The virus-driven degradation of messenger RNA is clearly linked to frontotemporal dementia (FTD) by altered language, personality, behavior, cognition and motor function. What causes FTD? If the virus-driven degradation of messenger RNA causes all pathology, I would expect to find a link from microRNAs to the pathology and to the effective treatment. The social … Until death: Virus-driven failure of multisensory integration (2)
