Do not call me Ishmael (4)

By: James V. Kohl | Published on: February 4, 2019

Summary: This interaction links the food energy-dependent pheromone-controlled creation of enzymes and receptors to biophysically constrained viral latency via the amino acid substitutions that differentiate all cell types in all individuals of all living genera.

CD4 receptor diversity in chimpanzees protects against SIV infection (2/4/19)

Reported as: Diversity in the CD4 receptor protects chimpanzees from infection by AIDS-like viruses

…chimpanzees have evolved several mutations in this CD4 domain that blocks this interaction…

The team found that these mutations include amino acid changes in contact residues as well as the addition of bulky sugar molecules, called glycans, at the CD4-envelope binding interface. “Glycans on the chimpanzee CD4 clash with glycans on the SIV envelope, which impedes virus entry into the cell,” said co-first author Frederic Bibollet-Ruche, Ph.D., a research assistant professor of Microbiology in Hahn’s lab. This type of glycan-glycan interaction has not been seen before as an anti-viral mechanism”.

This interaction links the food energy-dependent pheromone-controlled creation of enzymes and receptors to biophysically constrained viral latency via the amino acid substitutions that differentiate all cell types in all individuals of all living genera.

This team does not seem to know the difference between an amino acid substitution and a mutation. They must all be biologically uninformed science idiots who got their example of human idiocy past the reviewers at PNAS.

Do you know how peptides (chains of amino acids) are created? See for comparison:

Researchers may have solved origin-of-life conundrum

…the conditions that produce nucleic acid precursors also create… natural amino acids and lipids. That suggests a single set of [light activated] reactions [gave] rise to most of life’s building blocks simultaneously.

Subscribe
Notify of
guest
0 Comments
Inline Feedbacks
View all comments

Want more on the same topic?

Swipe/Drag Left and Right To Browse Related Posts:
Pheromone-regulated genetic processes (1)
2 MIN READ
0
Codon optimality vs systemic fraud (9)
5 MIN READ
0
MicroRNA-mediated existential threats (6)
< 1 MIN READ
0
MicroRNA-mediated existential threats (2)
2 MIN READ
0
Photonics in Forensics (8)
4 MIN READ
0
microRNA-mediated biodiversity (4)
2 MIN READ
0
“The Darwin Code: Intelligent Design without God” (2)
< 1 MIN READ
0
RNAi 2002 to AI 2021 (8)
< 1 MIN READ
0
RNAi 2002 to AI 2021 (2)
3 MIN READ
0
Naturally attenuated viral endemicity (1)
4 MIN READ
0
Orchestrated death: Kevin J. Mitchell
2 MIN READ
0
microRNA-mediated election cycles (5)
5 MIN READ
0
microRNA-mediated election cycles (4)
4 MIN READ
0
microRNA-mediated replication cycles (10)
2 MIN READ
0
Quantum biology vs atheism (1)
< 1 MIN READ
0
Quantum Darwinism (5)
3 MIN READ
0
Impeaching the God of Abraham (7)
2 MIN READ
0
Impeaching the God of Abraham (5)
< 1 MIN READ
0
Life or death facts about theories (2)
< 1 MIN READ
0
Suffering and loss of life by “voting blue” (1)
2 MIN READ
0
microRNA-mediated quantum error correction (4)
2 MIN READ
0
microRNA-mediated quantum error correction (2)
5 MIN READ
0
Optoribogenetic-driven sympatric speciation (2)
< 1 MIN READ
0
Coherently organized healthy longevity (4)
2 MIN READ
0
The microRNA-mediated future of humanity (1)
3 MIN READ
0
CDC’s ignorance: from roots to shoots (3)
4 MIN READ
0
From Wuhan to you (1)
2 MIN READ
0
The tipping point (revisited): 95K (1)
< 1 MIN READ
0
The tipping point (revisited): 93K (1)
4 MIN READ
0
#SFN2019 to 2012: Hiding the facts (1)
3 MIN READ
0
Patented Creation vs Evolution of Disease (8)
3 MIN READ
0
Nutrient-dependent Pheromone-controlled cures (4)
2 MIN READ
0
Lewis Thomas (revisited): 90K (6)
3 MIN READ
0
Lewis Thomas (revisited): 90K (3)
2 MIN READ
0
Bastardized health care (1)
6 MIN READ
0
Weaponized health communication (5)
2 MIN READ
0
MicroRNA-mediated enhancer-promoter chemistry
6 MIN READ
0
Trump-hating advocates of vaccines + GMOs (2)
5 MIN READ
0
The tipping point (revisited): 87K (2)
3 MIN READ
0
The tipping point (revisited): Genetics & Genomics 2019
5 MIN READ
0
Ecological Adaptations: From Angstroms to Ecosystems (1)
4 MIN READ
0
Kohl and Francoeur at 25 (1)
2 MIN READ
0
Templeton funded virus first creationism
3 MIN READ
0
Epic failure of the FDA: Gottlieb resigns (1)
3 MIN READ
0
DS Wilson’s view of biophysically constrained life (2)
2 MIN READ
0
RNA processing and disease 2019 (1)
2 MIN READ
0
Ecological adaptation vs neo-Darwinian nonsense (5)
4 MIN READ
0
Darwin Day 2019 (2) #darwinday2019
4 MIN READ
0
Darwin Day 2019 (1) #darwinday2019
4 MIN READ
0
Do not call me Ishmael (2)
2 MIN READ
0
Biophysically constrained fast adaptations (1)
5 MIN READ
0
Light and life at base pair resolution (10)
4 MIN READ
0
Plant microRNAs regulate across-kingdom gene expression (2)
5 MIN READ
0
Science journalism: a threat to humanity (1)
3 MIN READ
0
The tipping point (revisited): 81,000 publications (1)
5 MIN READ
0
Light and life at base pair resolution (2)
2 MIN READ
0
Hide and seek with science facts (7)
3 MIN READ
0
Hide and seek with science facts (6)
2 MIN READ
0
Hide and seek with science facts (1)
4 MIN READ
0
Bottom-up biology (revisited)
3 MIN READ
0
79,000 reasons to believe in biophysical constraints
8 MIN READ
0
Creation of an enzyme that kills theories (3)
8 MIN READ
0
Estranged ‘White Coat Notes’ blogger exposes human idiocy (2)
3 MIN READ
0
Laws of Biology vs no Laws of Physics (2)
3 MIN READ
0
Epigenetic inheritance of spatiotemporal regulation (3)
5 MIN READ
0
Ecological adaptations vs the randomness of evolution (3)
4 MIN READ
0
Environmental selection is natural selection (2)
2 MIN READ
0
The eternal significance of microRNAs (2)
3 MIN READ
0
Odor activation of ATP (2)
2 MIN READ
0
A mental health problem at the highest level (3)
7 MIN READ
0
The MicroRNAome Strikes Back: A Sokalian hoax (2)
6 MIN READ
0
The “walking fish” walks straight from quantum physics to quantum souls (5)
4 MIN READ
0
A Mathematical Model Links Quantum Physics to Quantum Souls (1)
6 MIN READ
0
Two retractions of human idiocy
2 MIN READ
0
Light activated error-free DNA repair (3)
3 MIN READ
0
Schrodinger’s answer to Schrodinger’s question
3 MIN READ
0
MicroRNAs and the Cassandra syndrome (revisited)
4 MIN READ
0
A null mutation and healthy longevity?
4 MIN READ
0
A mental health problem at the highest level
2 MIN READ
0
From base editing to RNA editing
2 MIN READ
0
Loss of energy as information (1)
3 MIN READ
0
Energy-dependent structure and function: Until death (5)
4 MIN READ
0
Predicting who wins the 2017 Nobel Prizes (7)
4 MIN READ
0
Until death: Virus-driven failure of multisensory integration (1)
4 MIN READ
0
Predicting who wins the 2017 Nobel Prizes (5)
2 MIN READ
0
Predicting who wins the 2017 Nobel Prizes (2)
4 MIN READ
0
Caught in an epigenetic trap: flag waving consequences
< 1 MIN READ
0
Evolutionary theories of epigenetic drift (2)
5 MIN READ
0
Science vs Secularism: Molecular Mechanisms or Math?
6 MIN READ
0
A fear of pheromones (revisited)
6 MIN READ
0
Host-derived creation of all pathology (2 of 2)
9 MIN READ
0
God vs host-derived creation of virus-driven pathology
6 MIN READ
0
Robert Sapolsky’s legacy of atheistic pseudoscientific nonsense
4 MIN READ
0
New Testament Book Cover Refutes Theistic Evolution
7 MIN READ
0
Energy-dependent physical and biophysical constraints (10)
8 MIN READ
0
Energy-dependent physical and biophysical constraints (5)
7 MIN READ
0
Energy-dependent physical and biophysical constraints (2)
4 MIN READ
0
Cell type assembly and the space-time continuum
2 MIN READ
0
Richard P. Feynman refuted theistic evolution
5 MIN READ
0
Epigenetic effects of stress by Bruce McEwen (2)
3 MIN READ
0
MicroRNAs GnRH and the failure of sex research
7 MIN READ
0
God’s shrinking role in salvation
8 MIN READ
0
Food energy-dependent epigenetic adaptation
11 MIN READ
0
Biologically uninformed biologists fight back and lose
3 MIN READ
0
Emily Witkin refutes theistic evolution
2 MIN READ
0
Pseudoscientists fail to refute theistic evolution
4 MIN READ
0
Francis S. Collins refutes theistic evolution
6 MIN READ
0
George Church refutes theistic evolution
5 MIN READ
0
Sudden death indel polymorphism
4 MIN READ
0
Anti-entropic virucidal energy as information
10 MIN READ
0
Bio-functional information
3 MIN READ
0
Controlled amino acid treatment of all pathology
4 MIN READ
0
Energy-dependent purifying selection / autophagy (6)
3 MIN READ
0
Top-down adaptation vs bottom-up evolution
6 MIN READ
0
Polycombic ecological adaptation as a science, not a theory (2)
12 MIN READ
0
The human virome (revisited)
4 MIN READ
0
Hecatombic evolution via oncocers and oncohistones
9 MIN READ
0
Life is energy-dependent task management
3 MIN READ
0
DNA repair via junk DNA (1)
5 MIN READ
0
MicroRNAs and sexual orientation
8 MIN READ
0
Cracking the Olfactory Code?
5 MIN READ
0
Energy-dependent RNA methylation (10)
4 MIN READ
0
Energy-dependent RNA methylation (1)
6 MIN READ
0
Wasted Templeton Funding (4)
3 MIN READ
0
Energy dependent RNA-mediated immunity (3)
8 MIN READ
0
Center stage RNA-mediated events (since 1996)
3 MIN READ
0
Stress-induced energy-dependent DNA repair
4 MIN READ
0
Teleophobes vs teleophiles: a recent history
2 MIN READ
0
Amino acid substitutions, stress, and human behavior
3 MIN READ
0
Epigenetic (re)programming of behavior
4 MIN READ
0
Does metabolism link beneficial mutations to cancer?
10 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs (3)
3 MIN READ
0
RNA-mediated theory killers (3)
7 MIN READ
0
Neo-Darwinism vs the neocortex
4 MIN READ
0
Nutrient-dependent trophic analogs
3 MIN READ
0
The virome, microbiome, replisome and supercoiled DNA
2 MIN READ
0
Neo-Darwinian logic is nonsense
3 MIN READ
0
Xist-ing on planet Earth
2 MIN READ
0
Keep the gay gene theory?
< 1 MIN READ
0
A “new” code enables ecological adaptation
4 MIN READ
0
Koonin: viruses killed neo-Darwinism
3 MIN READ
0
Decreased phenotypic variation: Faith in Facts
7 MIN READ
1
RNA-mediated gene duplication, fixation, and ecological adaptation
6 MIN READ
0
Virus-driven death by evolutionary theory
3 MIN READ
0
Informing the biologically uninformed
< 1 MIN READ
0
Epigenetics: microRNAs effect an integrative pathway
4 MIN READ
0
Silencing genes and serious scientists
3 MIN READ
0
Graphic misrepresentations of ecological adaptation
2 MIN READ
0
Creating nothing but a theory
4 MIN READ
0
2 genes in 2 species (too expensive and too insignificant)
11 MIN READ
0
Correctly modeling biological energy
2 MIN READ
0
Correctly modeling ecological adaptation
4 MIN READ
0
Questions about life’s diversity
21 MIN READ
0
Let there be anti-entropic light (1)
11 MIN READ
0
Military combat training to fight disease
3 MIN READ
0
Beneficial microbes kill beneficial mutations
4 MIN READ
0
Constrained evolution is ecological adaptation
5 MIN READ
0
The future of physics predicts no future for evolutionary theory
3 MIN READ
0
Complex behaviors of cell types in cancer
6 MIN READ
0
In theory, or supported by experimental evidence?
5 MIN READ
0
Evolutionary theorists justify fear of the Ebola viruses
2 MIN READ
0
Color vision refutes the evolutionary dogma of gene duplication
4 MIN READ
0
Ecological variation and niche construction: 1, 2, 3
6 MIN READ
0
Do bacterial proteins evolve?
3 MIN READ
0
Probable changes in connectivity
2 MIN READ
0
Memory of repression and memory of behavior (2)
< 1 MIN READ
0
Some neuroscientists think a mutation led to human language development
< 1 MIN READ
0
Is the problem an internet echo or Feierman's ethics?
2 MIN READ
0
RNA-mediated ecological adaptation is not evolution
2 MIN READ
0
Mechanisms that are not understood increase clarity
4 MIN READ
2
Nutrient-dependent erythropoiesis and anemia
6 MIN READ
0
A microRNA-mediated mechanism that is epigenetically inherited
2 MIN READ
0
Epimutations: Attacking pseudoscientific dogmas
4 MIN READ
0
The quantum biology of consciousness
3 MIN READ
0
Chromosomal rearrangements and ecological adaptations
4 MIN READ
0
96 fixed amino acid substitutions, not 96 genes
6 MIN READ
0
Alternative splicings (very technical)
2 MIN READ
0
Seeds of life: astrobiological theory and mutations theory
3 MIN READ
0
Functional coding variants are not mutations
2 MIN READ
0
Random mutations: nothing adaptive in 3 billion years
< 1 MIN READ
0
A “new” view of evolution sans mutations
< 1 MIN READ
0
Adaptive evolution: Genetic selection against some disorders
3 MIN READ
0
Constraints on mutational drift
< 1 MIN READ
0
Random mutations theory and pervasive mosaic evolution (the brain)
2 MIN READ
0
Random mutations theory and pervasive mosaic evolution (the body)
2 MIN READ
0
Epigenetic effects on chromatin and regulatation of gene expression (in Archaea?)
2 MIN READ
0
The genetics myth meets the great pheromone myth
2 MIN READ
0
A key mutational event? That’s not very likely.
3 MIN READ
0
Creation vs Evolution: Expression of a newly found gene
2 MIN READ
0
More complicated than 1-2-3
2 MIN READ
0
Docosahexaenoic acid vs. creative use of mutations in natural selection
3 MIN READ
0
Biological facts constrain proponents of random mutations theory
2 MIN READ
0
Pre-existing genetic variability or random mutations: a matter of priorities and choices
2 MIN READ
0
Creation vs Evolution? Pre-existing genetic variation, not random mutation
2 MIN READ
0