Autophagy automagically prevents cancer (2)
Study suggests how high blood pressure might contribute to Alzheimer’s 1/28/19, and this report on another article from the same issue of Nature Communications on 11/19/18 was also reported on 1/28/19 as New knowledge about the interactions of messenger RNAs and micro-RNAs during brain development
…imbalance between cell types… can lead to this disease… and… this imbalance results from these two modes—mRNA and miRNA—not being correctly aligned.
On 1/27/19, in Autophagy automagically prevents cancer (1), I attested to the fact that the alignment is energy-dependent and the energy biophysically constrains viral latency.
The response from MedicalXpress was immediate. After more than a two-month delay, they published news on the articles that linked my invited review of nutritional epigenetics from human colonization of North and East Asia to colonization of the New World.
Only one food energy-dependent pheromone-controlled base pair change and fixation of one amino acid, the EDAR V30A variant, was required. The facts about how the microRNA/messenger RNA balance biophysically constrains energy-dependent alignment were detailed in Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems
This angstroms to ecosystems model of ecological adaptation links nutrient energy-dependent epigenetic effects on base pairs and amino acid substitutions to pheromone-controlled changes in the microRNA/messenger RNA balance and chromosomal rearrangements via the physiology of reproduction in species from microbes to humans.
Thanks to Kosik’s group (i.e., Nowakowski et al., 2018) for recapitulating the facts known to all researchers who have linked autophagy to healthy longevity in all living genera.
See for comparison: Regulation of cell-type-specific transcriptomes by microRNA networks during human brain development
Had Kosik’s group linked the creation of sunlight to microRNA biogenesis and all biodiversity on Earth via the physiology of reproduction, they would have eliminated the neo-Darwinian pseudoscientific nonsense touted in their past works.
Instead, see: Study reveals evolution at work: Analyses elucidate a part of the brain particular to primates 2/27/14
Rather than admit that all serious scientists know how the energy-dependent microRNA/messenger RNA balance is linked to the prevention of all virus-driven diseases, pseudoscientists and biologically uninformed science journalists publish results like these:
Germs in Your Gut Are Talking to Your Brain. Scientists Want to Know What They’re Saying 1/28/19
…experiments have proven remarkably encouraging… [but] scientists don’t want to encourage the notion that microbiome-based cures for diseases like Parkinson’s are around the corner.”
Microbiome-based cures for diseases like Parkinson’s and all other forms of pathology link microRNA biomarkers from energy-dependent biophysical constraints on RNA interference to prevention and/or effective treatments of all diseases.
See also: Humans colonized diverse environments in Southeast Asia and Oceania during the Pleistocene 1/28/19
New review compares the regional adaptations of humans and those of other hominin species to add support to the argument that our species is ecologically unique.
The adaptations are food energy-dependent. Light-activated microRNA biogenesis is required for the growth of food, and species-specific pheromones are produced when enzymes metabolize the food that links the pheromones to biophysically contrained viral latency in species from microbes to humans via autophagy.
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RNA-mediated DNA modifications
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0
Ricki Lewis’ Time Machine
5 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (5)
10 MIN READ
0
A failed theory of cancer: two more decades of pseudoscience
5 MIN READ
0
Finding peace and π in the light of H bond energy (2)
8 MIN READ
0
Assumptions prove ignorance
5 MIN READ
0
Controled Stem Cell Expansion
3 MIN READ
0
Mystery machine vs model (3)
2 MIN READ
0
Thermotolerance and Longevity
57 MIN READ
0
Ecology replaces the extended evolutionary synthesis
4 MIN READ
0
Viruses, amino acids, and somatic cell types (3)
9 MIN READ
0
“New” epigenetic mechanism for lifelong learning?
3 MIN READ
0
Unconscious affect (revisited)
2 MIN READ
0
Olfactory perception of genetic information
2 MIN READ
2
Epigenetic regulation of aging by glycine and GnRH
5 MIN READ
0
A lighting requirement for life
11 MIN READ
3
Scientists lose. A sci-fi author gains credibility
2 MIN READ
0
Retinoic acid + one receptor regulate the genome
3 MIN READ
0
Epigenetics: microRNAs effect an integrative pathway
4 MIN READ
0
How to find a “holy grail” under your nose
3 MIN READ
0
Finding odor and taste receptors everywhere
6 MIN READ
0
Re-inventing a completely new thing
4 MIN READ
0
Nutrient-dependent RNA interference
4 MIN READ
0
Viruses and ecologically adapted animals
2 MIN READ
0
RNA-directed gene choice
5 MIN READ
0
Walk towards the light
< 1 MIN READ
0
Two types of microRNA are not double agents
2 MIN READ
0
Imagining that data historically supports evolutionary theory
7 MIN READ
0
All of "like kind" in the (bigger) family
6 MIN READ
1
Environment epigenetically shapes the immune system
3 MIN READ
0
From Hydra to humans vs a Lakatosian research program
4 MIN READ
0
Unified nutritional and molecular mechanisms
9 MIN READ
0
Atoms to ecosystems: Evolutionary theory vs the coelacanth
6 MIN READ
0
Extensive molecular evidence vs ridiculous theories
2 MIN READ
0
Dual genomes: exposing the evolution industry
5 MIN READ
0
Thermodynamic constraints and ecological adaptations sans evolution
6 MIN READ
0
Eliminating correlations from evolutionary ecology
6 MIN READ
0
The key to science: experimental evidence
5 MIN READ
0
Ecological adaptations reported as evolution in insects and mammals
4 MIN READ
0
Nothing new under the sun, except pseudoscientific nonsense
6 MIN READ
0
We need pattern recognition, not a prologue
6 MIN READ
0
Sexual differentiation of cell types in plants
2 MIN READ
0
No understanding of biodiversity
2 MIN READ
0
Understanding physical forces of ecological variation and adaptation
< 1 MIN READ
0
Eliminating evolutionary theory
3 MIN READ
0
2014 and 2004 Nobel Prize in Medicine
3 MIN READ
0
Unassailable evidence vs assumptions
4 MIN READ
0
Forces of "Nature" limit dissemination of information
4 MIN READ
0
Systems biology and memory disorders
3 MIN READ
0
Physics, Chemistry, and Molecular biology (PCMb)
2 MIN READ
0
Physics denied; pseudoscientific nonsense accepted
2 MIN READ
0
Ecological variation and niche construction: 1, 2, 3
6 MIN READ
0
Epigenetically-effected metabolic shifts and ecological adaptations
3 MIN READ
0
Evolving DNA before RNA
4 MIN READ
0
RNA-directed DNA methylation and RNA-mediated events
5 MIN READ
1
Quantum physics meets Evolutionary Psychology News
2 MIN READ
0
Insect homology and diversity attributed to mutations
2 MIN READ
0
Comparing divergent model organisms
2 MIN READ
1
Order and disorder: Ecological adaptations not mutations
6 MIN READ
0
Drunks and Monkeys: Pseudoscientific nonsense
2 MIN READ
0
The quantum biology of consciousness
3 MIN READ
0
Nutrition, pheromones and cancer (2)
2 MIN READ
0
Don't tell the Creationists
2 MIN READ
0
Understanding the role of mutations and evolution
4 MIN READ
0
Pheromones and cancer
4 MIN READ
0
Adaptive evolution: Genetic selection against some disorders
3 MIN READ
0
Music to our ears and song in birds: a common sense approach
2 MIN READ
0
Thinking about what we know (or not)
2 MIN READ
0
Increased chemosensory ability and eye regression: a “Just-So” fish story
2 MIN READ
0
Non random adaptive evolution
< 1 MIN READ
0
Epigenetic effects underlie sexual preferences (duh, and food preferences)
2 MIN READ
0
The challenges of a Darwinian approach to anything
3 MIN READ
0
Fatal attractions: a fear of pheromones
2 MIN READ
0
The Knowing Nose: Chemical Signals Communicate Human Emotions
< 1 MIN READ
0
Human Pheromones: Epigenetic Effects of Odors and Their Affects on Behavior
2 MIN READ
0
Pheromonemotionally speaking
2 MIN READ
0
Playing with breasts (e.g, with a new THEORY of why only heterosexual men love them)
3 MIN READ
0
Chemical conditioning of food reward and drug addiction
< 1 MIN READ
0
Insect to human cognition
2 MIN READ
0
Human pheromones, nutrition, DNA, epigenetics (2)
2 MIN READ
0
Pheromones and multicellularity
< 1 MIN READ
0
The role of food in the evolution of maternal and paternal care in avian species
2 MIN READ
0
Human pheromones are like sugar (and spice)
< 1 MIN READ
0
Smelling the difference between young and old
< 1 MIN READ
0
A thought experiment
3 MIN READ
0
Passing On Stress
2 MIN READ
0
More than speculation: adaptive evolution in species from microbes to man
2 MIN READ
0
Human pheromones and your immune system
< 1 MIN READ
0
Human Pheromones: extremely technical representation of the concept
2 MIN READ
0
Human Pheromones in Socioaffective Neuroscience & Psychology
2 MIN READ
0
Pheromones and the “Bruce effect” in wild or domesticated horses and primates
2 MIN READ
0
They are what they eat, and so are we
2 MIN READ
0
How memory works
2 MIN READ
0
A Preoccupation With Modesty…
2 MIN READ
0
Pheromones: from microbes to man
< 1 MIN READ
0
The biology of behavior: Seeing more clearly
< 1 MIN READ
0
Explaining a good theory
< 1 MIN READ
0
Effects of pheromones on menstrual synchrony and a gay man
2 MIN READ
0
Did viruses make mammals communicate with pheromones?
2 MIN READ
0
Do Pheromones Play a Role in Our Sex Lives: Scientific American
< 1 MIN READ
0
The cause of colony collapse could be a message for all of us
< 1 MIN READ
0
Human Pheromones: 2010 Powerpoint slides and 2011 poster presentation
2 MIN READ
0
Epigentics and the baby connectome
2 MIN READ
0
Cookbook chemistry: food odors and hormones
< 1 MIN READ
0
Epigenetics and the connectome
2 MIN READ
0
Human pheromones and food odors
< 1 MIN READ
0
Misrepresentations of biologically based cause and effect:
3 MIN READ
0
Pheromones and the Evolution of Drug Resistance
< 1 MIN READ
0
Cause and effect in biology
< 1 MIN READ
0
Human pheromones provide clues to personality
< 1 MIN READ
0
How pheromones work (in 57 words or more)
< 1 MIN READ
0
The Demise of Guys
< 1 MIN READ
0
The epigenetics of food choice and mate choice
< 1 MIN READ
0
Pheromones and detectable odors
2 MIN READ
0
Pheromone-enhanced behavior in sexually inexperienced females
2 MIN READ
0
The “yuck” factor: aversion to social odors?
2 MIN READ
0
Avian ‘Axe effect’ attracts attention of females and males
2 MIN READ
0
Scents of Adolescence: Are you blind?
< 1 MIN READ
0
Human pheromones: social odors and food odors
< 1 MIN READ
0
Honeybees, food odors, and perfume
< 1 MIN READ
0
Pheromones and a realistic model of sexual differentiation
3 MIN READ
0
Avian recognition of human faces
< 1 MIN READ
0
Human Pheromones Affect Women's Behavior
2 MIN READ
0
A lesser role for olfaction and pheromones in humans?
1 MIN READ
0
Creating a Myth
< 1 MIN READ
0
Pheromones in birds, other mammals, and us
< 1 MIN READ
0
The great pheromone myth revisited (including biological factors in the development of sexuality)
4 MIN READ
0
The great pheromone myth revisited (including biological factors in the development of sexuality)
4 MIN READ
0
Social selection: genetic contribution of viruses to life on earth
< 1 MIN READ
0
Wikipedia comments by James V. Kohl
5 MIN READ
0
Excellent new book about pheromones
< 1 MIN READ
0
Study design| Psychophysics experiment | Perspective on conditioning
< 1 MIN READ
0
Adrenarche and odor preferences
2 MIN READ
0
For ethologists: Observation does not trump molecular biology
2 MIN READ
0
Human Pheromones and The Philosophy of Science
2 MIN READ
0
Genes, Hormones, and Behavior (for other scientists)
4 MIN READ
0
Love at first sight: Selective breeding, pheromones, and Divine intervention
3 MIN READ
0
A fundamental attribution error: Love at first sight
3 MIN READ
0
Human Pheromones
< 1 MIN READ
0
Pheromones and olfaction in the birds and the bees: from yeasts to you
2 MIN READ
0
Debunking the myth of pheromones
< 1 MIN READ
0
Tears and fears of pheromones
2 MIN READ
0
Exotic Pheromones and Concentrates
2 MIN READ
0
Marketing vs. the truth about human pheromones
2 MIN READ
0
Epigenetics, science fiction, and scientific fact
2 MIN READ
0
Results: increased flirtatious behavior and self-reported attraction
2 MIN READ
0
Is it what he or she sees in you, or is it your pheromones?
2 MIN READ
0
Product comparisons and human pheromone sciences
3 MIN READ
0
Conditioning of the human pair bond by human pheromones
< 1 MIN READ
0
Conditioned sexual arousal to odor
2 MIN READ
0
Scent signals
< 1 MIN READ
0
Pheromones and signature mixtures
2 MIN READ
0
Comparative biology of pheromonal communication
< 1 MIN READ
1
Food preferences and mate preferences
< 1 MIN READ
0
Presentation on Human Pheromones delivered on August 3, 2010
2 MIN READ
0
Sold on the human VNO?
< 1 MIN READ
0
Effects of pheromones attributed to touch (in mice)
< 1 MIN READ
0
How pheromones work by James V. Kohl
2 MIN READ
0
Pheromones of pregnant women effect prolactin in men
< 1 MIN READ
0
Another book author's comment on "The Great Pheromone Myth"
< 1 MIN READ
0
An attempt to change the concept
< 1 MIN READ
0
Luteinizing hormone, sex, and smell (18 years later)
2 MIN READ
0