The eternal significance of microRNAs and the Vietnam Memorial (2)
(click to enlarge)
Summary: Quantized energy as information has been linked from what organisms eat to biophysically constrained membrane protein construction in the context of viral latency and healthy longevity. Cryoelectron microscopy (aka electron cryomicroscopy for obfuscation) clearly links what is known about the virus-driven degradation of messenger RNA to all pathology or from energy-dependent RNA-mediated DNA repair to species survival.VIDEO VIDEO Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems
The plausibility and ecological validity of Kohl’s Laws in the context of Darwin’s ‘conditions of life’ can be compared to theories about biologically-based cause and effect in the context of species diversity. In mammals, for example, the explanatory power of a model of ecological variation and biophysically constrained nutrient-dependent pheromone-controlled ecological adaptations became clear with companion papers published in 2013. See for review [26].
The companion papers [159,160] told a new short story of ecological adaptations. In the context of climate change and changes in diet, the story began with what probably was a nutrient-dependent base pair change and a variant epiallele that arose in a human population in what is now central China. Apparently, the effect of the epiallele was adaptive and it was manifested in the context of an effect on sweat, skin, hair, and teeth. In another mammal, such as the mouse, the effect on sweat, skin, hair, and teeth is probably due to a nutrient-dependent epigenetic effect on hormones responsible for the tweaking of immense gene networks that metabolize nutrients to pheromones.
The pheromones appear to control the nutrient-dependent epigenetically-effected hormone-dependent organization and hormone-activation of reproductive sexual behavior in mammals such as mice and humans, but also in invertebrates and in microbes as previously indicated. The ecological adaptations, which appear to be manifested in the human population are detailed in these two reports [159,160]. The ecological adaptations are likely to be nutrient-dependent and pheromone-controlled. If so, ecological variation probably leads to ecological, social, neurogenic, and socio-cognitive niche construction, which is manifested in increasing organismal complexity and species diversity. If not, there may be something as yet unknown about mutations and evolution that makes sense in the light of what is known about nutritional epigenetics and the molecular biology of species from microbes to man.
See for comparison: Guide to the classics: Darwin’s On the Origin of Species
Throughout the book, he repeatedly addresses creationist views and shows that they are incompatible with the evidence.
He started with God’s creation of the “conditions of life” and linked them to ecological adaptations via his observations that all organisms need to eat or species become extinct. Biologically uninformed science idiots bastardized his claims by putting “natural selection” first. Feynman put their claims into the context of this lecture on food energy and human idiocy.conditions of life , see:4
IF under changing conditions of life organic beings present individual differences in almost every part of their structure, and this cannot be disputed; if there be, owing to their geometrical rate of increase, a severe struggle for life at some age, season, or year, and this certainly cannot be disputed; then, considering the infinite complexity of the relations of all organic beings to each other and to their conditions of life, causing an infinite diversity in structure, constitution, and habits, to be advantageous to them, it would be a most extraordinary fact if no variations had ever occurred useful to each being’s own welfare, in the same manner as so many variations have occurred useful to man. But if variations useful to any organic being ever do occur, assuredly individuals thus characterised will have the best chance of being preserved in the struggle for life; and from the strong principle of inheritance, these will tend to produce offspring similarly characterised. This principle of preservation, or the survival of the fittest, I have called Natural Selection.
5
“…the greater variability of species having wider ranges than of those with restricted ranges, lead to the conclusion that variability is generally related to the conditions of life to which each species has been exposed during several successive generations.”
“When a variation is of the slightest use to any being, we cannot tell how much to attribute to the accumulative action of natural selection, and how much to the definite action of the conditions of life .”
“Instances could be given of similar varieties being produced from the same species under external conditions of life as different as can well be conceived; and, on the other hand, of dissimilar varieties being produced under apparently the same external conditions. Again, innumerable instances are known to every naturalist, of species keeping true, or not varying at all, although living under the most opposite climates. Such considerations as these incline me to lay less weight on the direct action of the surrounding conditions, than on a tendency to vary, due to causes of which we are quite ignorant.”
6
“By my theory these allied species are descended from a common parent; and during the process of modification, each has become adapted to the conditions of life of its own region, and has supplanted and exterminated its original parent-form and all the transitional varieties between its past and present states.”
Darwin’s theory linked his conditions of life to energy-dependent ecological adaptations via construction of cell membranes in all cell types of all individuals of all living genera. Now is the time to stop biologically uninformed theorists from continuing to tout their pseudoscientific nonsense and accept the fact that creationist views are incompatible with the experimental evidence of top-down energy-dependent causation and biophysically constrained effects on cell membranes linked to differences in morphological and behavioral phenotypes.
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5
0
The emergence of light as energy from a life-giving star (2)
2
0
Milk-derived miRNAs, circulating microRNAs, DNA repair, and embryonic viability
2
0
God’s shrinking role in salvation (3)
9
0
God's shrinking role in salvation (3)
9
0
MicroRNAs GnRH and the failure of sex research
7
0
God’s shrinking role in salvation (2)
5
0
Food energy-dependent cell type differentiation (2)
10
0
Hard Science vs the neo-Darwinian “magic box”
9
0
MicroRNAs light up life
7
0
From E. coli to monkeys and mankind: Theories vs models (5)
5
0
From E. coli to monkeys and mankind: Theories vs models (4)
2
0
From E. coli to monkeys and mankind: Theories vs models (2)
6
0
Food energy-dependent epigenetic adaptation (2)
< 1
0
Food energy-dependent epigenetic adaptation
11
0
Energy-dependent epigenetic translation to mRNA stability (2)
5
0
Energy-dependent epigenetic translation to mRNA stability
8
0
Nothing evolved into all biodiversity on Earth
4
0
Energy as information and constrained endogenous RNA interference (4)
7
0
What energy source do proteins prefer?
6
0
Draining the academic swamp of parasites
3
0
The death of human ethology via ecology
7
0
The death of CRISPR; long live endogenous RNAi
5
0
The Virus-Driven Suicide March for Science
5
0
Open Science: Closed to facts about microRNAs
6
0
Viruses in pathogenic variants disrupt alternative splicings (2)
3
0
Respiration-dependent endogenous RNA interference
4
0
Cytosis: Biology Content
7
0
Light-activated feedback loops vs self-organization of ecosystems
7
0
Sal Giardina: apologetics revisited
8
0
Who will kill the billion dollar baby? Bill Gates or Donald Trump
3
0
Food for thought: Penrose v Ellis (3)
4
0
Magnussen’s “Faith fools” keep the faith
3
0
Proof: Sunlight is energy as information
< 1
0
Energy-dependent pheromone-controlled entropy (1)
4
0
The essence of precision medicine: drug targets or healthy longevity?
4
0
The essence of precision medicine
4
0
Allen Institute confirms food energy is information
6
0
RNA-mediated adult learning, memory, and neurogenesis
3
0
Energy-dependent allelic imbalances, viruses, and pathology
3
0
Theistic evolutionists fight back and lose (3)
4
0
Theistic evolutionists fight back and lose (2)
4
0
Theistic evolutionists fight back and lose
4
0
Charles Darwin refutes theistic evolution
2
0
Bill Gates refutes theistic evolution (sequel)
8
0
Bill Gates refutes theistic evolution
4
0
Emily Witkin refutes theistic evolution
2
0
Pseudoscientists fail to refute theistic evolution
4
0
Stuart Kauffman refutes theistic evolution
3
0
May the anti-entropic force of sunlight be with you
4
0
Francis S. Collins refutes theistic evolution
6
0
Energy is information. Objections over ruled. You’re fired!
7
0
Happy Darwin Day (2017)
4
0
George Church refutes theistic evolution (3)
5
0
George Church refutes theistic evolution (2)
2
0
George Church refutes theistic evolution
5
0
Bacteriophages prove evolution is a lie
2
0
Mitochondria do not adapt
2
0
Energy as information and constrained endogenous RNA interference (2)
2
0
Virus-driven energy theft and premature death
3
0
Fighting for virus-driven pathology
5
0
Dobzhansky 1973 and precision medicine (5)
3
0
Dobzhansky 1973 and precision medicine (4)
5
0
Atomic theory vs facts about hydrogen-atom transfer
4
0
Trump’s appeal to common sense
2
0
Twisted theories and weaponized facts
3
0
Mutations: the “driving force” behind human brain complexity?
6
0
Mutations: the "driving force" behind human brain complexity?
6
0
Anti-entropic energy and the “Music of Life”
3
0
Anti-entropic energy and the "Music of Life"
3
0
Evolved patterns of brain stimulation
3
0
Energy-dependent hydrogen bonds in supercoiled DNA
7
0
Energy-dependent chirality (2)
3
0
Energy-dependent chirality
6
0
Energy-dependent alternative splicings 1996 – 2016 (2)
5
0
Vietnam Veterans and others with glioblastoma
3
0
Energy-dependent sensory maps (1996-2016)
5
0
Energy-dependent alternative splicings 1996 – 2016
12
0
Energy-dependent oscillating gene networks organize life
4
0
Re-inventing mutation-driven evolution (2)
4
0
Re-inventing mutation-driven evolution
3
0
Anti-entropic virucidal energy as information
10
0
Bio-functional information
3
0
Expunging the distinguished public
2
0
Explorers who do not know what is known (2)
6
0
Autophagy is the antiphage defense strategy
3
0
Tasting light links energy from creation to adaptation
9
0
Combating evolution: Battlefield medicine vs politicized science
6
0
The futility of The Battlefield FB group
10
0
Metabolic Phenotyping Research
2
0
Phylogenetic similarity sans energy
2
0
Energy-dependent coulombic, autophagic, polycombic healthy longevity
4
0
Light, behavior and autophagy, a gender-specific risk factor
4
0
Controlled amino acid treatment of all pathology
4
0
Energy-dependent purifying selection / autophagy (3)
2
0
Energy-dependent purifying selection / autophagy (6)
3
0
Energy-dependent purifying selection / autophagy
2
0
Building delicious base pairs in class. It’s elementary Watson and Crick
3
0
Building delicious base pairs in class. It's elementary Watson and Crick
3
0
Virus-driven mutation or amino acid substitution
5
0
Epigenetically effected energy-dependent fluorescence (2)
6
0
Epigenetically effected energy-dependent fluorescence
5
0
Epigenetics and autophagy vs mutations and evolution (7)
3
0
Epigenetics and autophagy vs mutations and evolution (3)
< 1
0
From Precis to Proof in 6000 years (2)
5
0
From Precis to Proof in 6000 years
9
0
Coulombic interactions facilitate polycombic adaptation
5
0
Polycombic ecological adaptation as a science, not a theory (2)
12
0
Polycombic ecological adaptation as a science, not a theory
3
0
80 years of causal analysis (1936 – 2016)
11
0
The natural success of RNAi and failed treatment
7
0
Did evolution autophosphorylate your kinases? (2)
5
1
Life is energy-dependent task management (2)
3
0
Life is energy-dependent task management
3
0
Hypothesis free pseudoscience vs facts (3)
3
0
Hypothesis free pseudoscience vs facts (1)
5
0
Hydrogen-atom energy in DNA base pairs
6
0
DNA repair via junk DNA (2)
5
0
The Aquatic Ape / Waterside Ape divergence
6
0
Light energy-dependent active motifs
6
0
Light energy-induced base pair changes (2)
4
0
Light energy-induced base pair changes (1)
6
0
How did the innate immune system evolve?
4
0
The Aquatic Ape: New evidence?
4
0
Protecting 4 billion people from virus-driven entropy
< 1
0
Lawless evolution: No physics
4
0
Virus-driven energy theft: honeybee model
3
0
Antithetical conclusions (7)
3
0
Antithetical conclusions (5)
4
0
RNAi: From magic bullet to billion dollar baby
4
0
GC-rich neo-Darwinian train wreck
5
0
From angstroms to ecosystems
7
0
Food supplement or licensed immunostimulant?
6
0
Virus-driven downsizing of the human brain (3)
4
0
The end of neo-Darwinism
5
0
Biophotonics, glycobiology, quantized biodiversity
4
0
The Origin of Information (2)
6
0
The tipping point? 50,000 publications (5)
3
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution
6
0
Did “Nature” kill Steve Jobs? (3)
10
0
Invisible dark matter
< 1
0
Did “Nature” kill Steve Jobs? (2)
6
0
Did “Nature” kill Steve Jobs?
3
0
Virus-driven downsizing of the human brain (2)
< 1
0
Placing boundaries where none exist
< 1
0
Virus-driven downsizing of the human brain
2
0
Virus altered thermodynamic stability
< 1
0
RNA methylation, learning, memory and behavior,
< 1
0
Innate immunity and multiplexing
7
0
RNA methylation (2)
7
0
Amino acids and virus penetration
3
0
Major transition ends use of silly theories
5
0
Masters of deception about nature (2)
7
0
Masters of deception about nature
8
0
The Mind’s Eyes (revisited)
10
0
Cracking the Olfactory Code?
5
0
RNA methylation, behavior, and disease
6
0
Energy-dependent RNA methylation (9)
2
0
Energy-dependent RNA methylation (8)
4
0
Energy-dependent RNA methylation (7)
7
0
Energy-dependent RNA methylation (6)
9
0
Energy-dependent RNA methylation (5)
3
0
Energy-dependent RNA methylation (3)
10
0
Energy-dependent RNA methylation (2)
5
0
Countdown to Genetics and Genomics
< 1
0
Energy-dependent creation and entropy
4
0
RNA splicing, genetic variation, and disease
2
0
Wasted Templeton Funding (3)
2
0
Molecular Diagnostics: What is unprotected life (4)
2
0
Ricki Lewis’ Time Machine (4)
8
0
Creating nutrient-dependent life with enough genes to survive
3
0
Selective reporting of inferences: examples of pseudoscience
14
0
Ignore the evidence: Rachel Feltman
5
0
Stress-linked population-level history dependence
5
0
Energy dependent RNA-mediated immunity (3)
8
0
Hybrids: making microbes and Democrats into monkey’s uncles?
11
0
The Light and Darkness of “Evolution 2.0”
11
0
Cancer: Evolution 2.0’s Blind Spot
13
0
Hydrogen-atom transfer in DNA base pairs (5)
10
0
Blood test links atoms to ecosystems
2
0
Stress-induced energy-dependent DNA repair
4
0
Epigenetic (re)programming of behavior
4
0
NORAD: air defense and defense against genomic entropy
7
0
RNA-mediated theory killers (4)
9
0
RNA-mediated theory killers (2)
8
0
A two-faced protein enables RNA-mediated DNA repair (3)
8
0
Sulfated steroids and RNA-mediated identity codes
< 1
0
Sensationalizing no new mechanism
2
0
Multi-omic analysis features (SNPs, miRNA)
3
0
Natural selection: an anti-entropic force?
2
0
Olfaction & the octopus and human genomes (2)
4
0
Ecology replaces the extended evolutionary synthesis
4
0
MicroRNA controlled growth and brain development
7
0
Theoretically, purifying selection is evolution
< 1
0
What if Darwin was not still dead?
2
0
How fast can evolutionary theory be changed?
5
0
Mute points: most are afraid to mention them
6
0
Beneficial microbes kill beneficial mutations
4
0
A single amino acid substitution differentiates cell types of E. coli
3
0
Meaningful dialogue, anonymous fools and idiot minions
4
0
Achiral GnRH: no prophesy, just prediction
9
0
We need pattern recognition, not a prologue
6
0
From deep time into real time: What evolutionary processes?
10
0
Genes and Race: Human History?
2
0
Darwinian theories vs Darwin's facts
2
0
Nutrient-dependent pheromone-controlled stickleback evolution
2
0
(click to enlarge)