The MicroRNAome Strikes Back: A Sokalian hoax (10)
Prepare to ask questions or intelligently discuss accurate representations of top-down causation by watching this:
The energy-dependent creation of the microRNAome protects the organized genomes of all living genera from the virus-driven degradation of messenger RNA that links mutations to all pathology.
See: The Bull Sperm MicroRNAome and the Effect of Fescue Toxicosis on Sperm MicroRNA Expression
MicroRNA present in mature sperm appears to not only be left over from spermatogenic processes, but may actually serve important regulatory roles in fertilization and early developmental processes. Further, our results indicate the possibility that environmental changes may impact the expression of specific miRNA.
We conclude that the enzymes involved took these alternatives by chance in independent populations that had already evolved distinct ion pumps. Our model offers a quantitatively robust explanation for why membrane bioenergetics are universal, yet ion pumps and phospholipid membranes arose later and independently in separate populations. Our findings elucidate the paradox that archaea and bacteria share DNA transcription, ribosomal translation, and ATP synthase, yet differ in equally fundamental traits that depend on the membrane, including DNA replication.
The microRNA-mediated creation of enzymes is quantized energy-dependent and biophysically constrained by phosphorylation in the context of food energy and the transgenerational epigenetic inheritance of all morphological and behavioral phenotypes in species from bacteria to primates. Membrane divergence in archaea occurs via the virus-driven degradation of messenger RNA, which links the loss of quantized energy from mutations to all pathology. The degradation of the cell membrane links archaea to L-forms, the last remnant of the life of a cell. See: The Inner Life of the Cell (video)
See also: Virus-mediated archaeal hecatomb in the deep seafloor (2016)
We show here for the first time the crucial role of viruses in controlling archaeal dynamics and therefore the functioning of deep-sea ecosystems, and suggest that virus-archaea interactions play a central role in global biogeochemical cycles.
So far as I know, none of the people who are presenting at “The Future of Biology” meeting have linked Schroedinger’s claims from the past to what is known about the conserved molecular mechanisms of energy-dependent biophysically constrained RNA-mediated cell type differentiation in species from microbes to humans. Even if they are not evolutionary theorists, most have not linked the energy-dependent fixation of RNA-mediated amino acid substitutions to increasing organismal complexity and some have even reversed what is known about top-down causation. For example, Nick Lane, like Gunter P. Wagner have used mathematical models of correlations.
See: Pervasive correlated evolution in gene expression shapes cell and tissue type transcriptomes
They start with this admission”
A major challenge for interpreting this data is that cell type transcriptomes may not evolve independently…
They seem to think they can use statistics and interpretations to address the challenge of facts about increasing organismal complexity.
Our study provides a statistical method to measure and account for correlated gene expression evolution when interpreting comparative transcriptome data.
See for comparison: From Fertilization to Adult Sexual Behavior and Nutrient-dependent/pheromone-controlled adaptive evolution: a model
The fact that what organisms eat has been linked from the food energy-dependent creation of enzymes, receptors, and hormones to the affect of hormones on behavior in all invertebrates and vertebrates was placed into the context of the cell biology game, Cytosis.
A board game taking place inside a human cell! Players compete to build enzymes, hormones and receptors and fend off attacking Viruses!
Why do I have only 29 new followers? Are theorists really that scared? If so, how will they help to prevent the next viral apocalypse, if it has not already started before September, 2018?
In the past nothing happened because serious scientists failed to acknowledge this fact: Feedback loops link odor and pheromone signaling with reproduction. The article was co-authored by LInda Buck. There is no mention of mutations or evolution and Linda Buck is scheduled to present what can best be described as a refutation of neo-Darwinian evolution.